Rapid Testing of Solvents Through Amber Bottles using an Agilent Vaya Handheld Raman Spectrometer

The Agilent Handheld Vaya Raman spectrometer is a pharmaceutical analysis system that can be used to perform material verification of a range of chemical solvents through amber bottles. Using spatially offset Raman spectroscopy (SORS) technology, Vaya can perform through-barrier identification tests and produce easily interpretable “pass/fail” results on the screen of the handheld device. The solvents tested in this study are commonly used in the synthesis of some biopharmaceuticals or during analytical testing of the quality attributes of biologics throughout the production process. Data are provided that demonstrate how the Vaya Raman can be used for rapid verification testing of raw materials in a warehouse, without the need to open any bottles.

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