Identification of Commercially Available Oligonucleotide Starting Materials Directly Through Containers
Handheld Raman spectrometers can selectively identify oligonucleotide starting materials, also known as phosphoramidites, directly through amber bottles. This application note discusses the theory and deployment of Agilent handheld Raman systems based on spatially offset Raman spectroscopy (SORS) for chemical ID verification of phosphoramidites in a good manufacturing practice (GMP) environment.
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