Characterization of a synthetic double stranded siRNA using high-resolution mass spectrometry
Aim of this Whitepaper:
Demonstrate the capability of separating and characterizing a double-stranded siRNA and its diastereomers using a Thermo Scientific™ Vanquish™ Horizon UHPLC system coupled with a Thermo Scientific™ DNAPac™ RP column, a Thermo Scientific™ Orbitrap Exploris™ 120 mass spectrometer, and Thermo Scientific™ BioPharma Finder™ software.
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