Formulation Handbook

Formulation Handbook

 

Formulation Handbook

Unlock the power of precision in pharmaceutical formulation with the Merck SAFC® Formulation Handbook. Designed for formulation scientists and pharmaceutical manufacturers, this comprehensive guide offers over 100 practical examples across a wide spectrum of dosage forms—from conventional and chewable tablets to ODTs, dry syrups, effervescent formulations and more.

The handbook dives deep into tried-and-tested methodologies including direct compression, dry and wet granulation, and emerging technologies such as 3D printing and continuous manufacturing. For each method, model formulations using common APIs (e.g., paracetamol, ibuprofen, telmisartan) are provided alongside detailed tablet properties, process parameters, and excipient recommendations.

Explore the unique performance advantages of Merck’s Parteck® excipients and the Emprove® Program, which supports regulatory compliance and risk assessment. Whether you’re troubleshooting solubility challenges, optimising compressibility, or exploring hot-melt extrusion, this handbook is a vital resource for accelerating development and maintaining high standards in pharmaceutical production.

What You’ll Gain:

  • Ready-to-use formulation templates for 150+ APIs
  • In-depth comparisons of excipient performance
  • Guidance on scale-up, regulatory support, and process adaptability
  • Insights into continuous and high-speed manufacturing strategies

Empower your pharmaceutical innovation with Merck’s science-driven formulation expertise.

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