Quantification of Tablets Containing Multiple APIs Using Transmission Raman Spectroscop
The ability to predict multiple constituents of a final dosage form in one fast, nondestructive measurement can reduce analysis time and cost significantly. This is especially beneficial when quantification of multiple active pharmaceutical ingredients (APIs) is required for tests such as content uniformity, assay, and identity (ID). This example, based on a common cold and flu product, demonstrates the quantification of five components (three APIs and two excipients) with a nine‑second measurement. Nominal concentrations for the APIs ranged from 1 to 85 % w/w
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